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. 2019 May 1;12(6):859–870. doi: 10.1016/j.tranon.2019.03.005

Figure 5.

Figure 5

Tumor tissue analysis of the regulatory network influencing metadherin expression.

(A) Correlation between NF-κB subunits and MTDH expression as derived from tumor tissue datasets. (B) Correlation analysis of c-Myc copy number aberration versus MTDH expression. There was a significant association between c-Myc copy number gains and MTDH mRNA expression (P < .05) among independent patient cohorts. Rho is Spearman's rank correlation coefficient. CNA is copy number aberrations. Genentech RNA-seq data (n = 211). The Cancer Genome Atlas (TCGA)–RNA-seq data (n = 87).