Supplementary Figure S1.

Survey of MTDH basal expression in MPM lines.

Basal expression of MTDH transcript in a panel of NCI MPM cell lines. LP9 is used as the reference normal cell line for MTDH quantitation. MCF-7 breast carcinoma cells are positive control of MTDH expression. qRT-PCR quantitated relative abundance of MTDH in epithelioid MPM lines, a biphasic MPM line, and a sarcomatoid MPM line. The frequency of cell line histologies reflects the pathologic distribution (and availability) of human MPM. H2452, MSTO-211H, and H2373 were chosen as representative cells in subsequent experiments.