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. 2019 Mar 21;10(5):1051–1059. doi: 10.1111/1759-7714.13038

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© 2019 The Authors. Thoracic Cancer published by China Lung Oncology Group and John Wiley & Sons Australia, Ltd

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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miR‐194 inhibits the proliferation, migration and invasion of non‐small cell lung cancer (NSCLC) cells. (a) Wound healing assay was used to detect the migration ability of A549 and H1299 cells. Cells were transfected with miR‐194 mimic or mimic control. HG+NC, HG+miR‐194. (b, c) Transwell assay was employed to examine the invasion ability of A549 and H1299 cells. The invasive cell number in each group was normalized to the control. Cells were transfected with miR‐194 mimic or mimic control, and miR‐194 inhibitor or inhibitor control. A549, H1299. (d,e) Cell counting kit‐8 and cell counting assay were used to examine the proliferation ability of A549 and H1299 cells. Cells were transfected with miR‐194 mimic or mimic control. NC, miR‐194. Data are reported as mean ± standard deviation of three independent experiments (*P < 0.05, t‐test).

Inline graphic — miR‐194 inhibits the proliferation, migration and invasion of non‐small cell lung cancer (NSCLC) cells. (a) Wound healing assay was used to detect the migration ability of A549 and H1299 cells. Cells were transfected with miR‐194 mimic or mimic control. HG+NC, HG+miR‐194. (b, c) Transwell assay was employed to examine the invasion ability of A549 and H1299 cells. The invasive cell number in each group was normalized to the control. Cells were transfected with miR‐194 mimic or mimic control, and miR‐194 inhibitor or inhibitor control. A549, H1299. (d,e) Cell counting kit‐8 and cell counting assay were used to examine the proliferation ability of A549 and H1299 cells. Cells were transfected with miR‐194 mimic or mimic control. NC, miR‐194. Data are reported as mean ± standard deviation of three independent experiments (*P < 0.05, t‐test).