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. 2019 Mar 23;110(5):1665–1675. doi: 10.1111/cas.13989

Figure 5.

Figure 5

Flowchart of programmed cell death ligand 1 (PD‐L1) expression regulation by epidermal growth factor receptor (EGFR) mutants through downstream signaling effectors phosphorylated (p‐)AKT, p‐ERK, nuclear factor‐κB (NF‐κB), and hypoxia‐inducible factor‐1α (HIF‐1α). IKK, IκB kinase