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Blood glucose and hemoglobin A1c (HbA1c) levels during pembrolizumab treatment. Urinalysis of glucose and ketone bodies are also shown. The administration of the ninth course was delayed for seven days as a result of the onset of fulminant type 1 diabetes mellitus (T1DM), and the 12th course was delayed for 35 days because of acute exacerbation of chronic obstructive pulmonary disease.
