Figure 2.

Overexpression of TPT1‐AS1 significantly promoted epithelial ovarian cancer (EOC) cell proliferation in vitro and in vivo. A, B, Cell Counting Kit‐8 (A) and colony formation assays (B) using the TPT1‐AS1‐overexpressing or knockdown ES‐2 and SKOV3 cells. C, The tumor growth curve and weights of the TPT1‐AS1‐overexpressing SKOV3 subcutaneous ovarian xenografts. D, Representative immunohistochemical (IHC) staining for Ki‐67 in subcutaneous xenograft tumor tissues. Scale bar, 50 μm. Data represent mean ± SD from 3 independent experiments. *P < 0.05, **P < 0.01 and ***P < 0.001