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. 2019 Mar 25;110(5):1573–1586. doi: 10.1111/cas.13984

Figure 5.

Figure 5

Promotion of the activation of PI3K/AKT and RAS signaling pathways by testis‐specific protein, Y‐linked 1 (TSPY1) in A549 and HepG2 cells. A, Western blot analysis shows higher levels of 3 key proteins (p‐AKT, p‐mTOR, and BCL2) of the PI3K/AKT signaling pathway in TSPY1‐overexpressing A549 and HepG2 cells relative to controls. B, Western blot analysis shows higher levels of 4 key proteins (p‐RAF‐1, p‐MEK1/2, p‐ERK1/2 and JUN) of the RAS signaling pathway in TSPY1‐overexpressing A549 and HepG2 cells relative to controls