Table 1. Events of genetically engineered food crops with enhanced disease resistance to microbial pathogens that have been approved for commercial production.
Data collected from The International Service for the Acquisition of Agri-biotech Applications (ISAAA) and the U.S. Department of Agriculture-Animal and Plant Health Inspection Service (USDA-APHIS). MOA, Ministry of Agriculture, China; ARS, Agriculture Research Service; EMBRAPA, the Brazilian Agricultural Research Corporation; CTNBio, the Brazilian National Technical Commission on Biosafety.
Crop Species | Developer | Initial Approval | Target Pathogen | Gene(s) Expresseda | References |
---|---|---|---|---|---|
Squash | Seminis and Monsanto | 1994 USDA | Watermelon mosaic virus 2 and zucchini yellow mosaic virus | Coat proteins | Tricoli et al., 1995 |
Squash | Seminis and Monsanto | 1996 USDA | Cucumber mosaic virus, watermelon mosaic virus 2, and zucchini yellow mosaic virus | Coat proteins | Tricoli et al., 1995 |
Papaya | Cornell University and the University of Hawaii | 1996 USDA | Papaya ringspot virus | Coat protein | Gonsalves, 1998, 2006 |
Potato | Monsanto | 1998 USDA | Potato leafroll virus | Replicase and helicase | Thomas et al., 1997; Kaniewski and Thomas, 2004 |
Sweet Pepper | Beijing University | 1998 MOA | Cucumber mosaic virus | Coat protein | Zhu et al., 1996 |
Potato | Monsanto | 1999 USDA | Potato virus Y | Coat protein | Newell et al., 1991; Kaniewski and Thomas, 2004 |
Tomato | Beijing University | 1999 MOA | Cucumber mosaic virus | Coat protein | Yang et al., 1995 |
Papaya | South China Agricultural University | 2006 MOA | Papaya ringspot virus | Replicase | Ye and Li, 2010 |
Plum | USDA/ARS | 2007 USDA | Plum pox virus | Coat protein | Scorza et al., 1994; Ilardi and Tavazza, 2015 |
Papaya | University of Florida | 2009 USDA | Papaya ringspot virus | Coat protein | Davis and Ying, 2004 |
Bean | EMBRAPA | 2011 CTNBio | Bean golden mosaic virus | +, − RNA of viral replication protein | Bonfim et al., 2007; Tollefson, 2011 |
Potato | J.R. Simplot | 2015 USDA | Phytophthora infestans (late blight) | Resistance protein | Foster et al., 2009 |
Only genes relevant to pathogen resistance are listed.