Table 4.
Comparison of blood renal parameters in 3 age groups.
| Study group | ||||||
|---|---|---|---|---|---|---|
| Deferoxamine | Deferasirox | Control | ||||
| Mean ± SD | Mean ± SD | Mean ± SD | p value | |||
| Age | Under 18 years old (n = 18) | GFR | 147.08 ± 28.40 | 125.12 ± 30.35 | — | 0.159 |
| BUN | 9.33 ± 3.01 | 14.40 ± 6.19 | 11 ± 2.55 | 0.161 | ||
| CREA | 0.57±0.05∗∗ | 0.66±0.13∗∗ | 0.68 ± 0.08 | 0.048∗∗ | ||
| Cystatin C | 92.42 ± 112.98 | 17.89 ± 4.47 | 20.14 ± 11.10 | 0.593 | ||
| GFR based on Cystatin | 2.37 ± 2.10 | 3.15 ± 0.77 | 3.91 ± 2.28 | 0.416 | ||
| 18 to 25 years old (n = 27) | GFR | 139.58 ± 27.04 | 130.67 ± 23.33 | 106.78 ± 15.78 | 0.053 | |
| BUN | 13.44±2.46∗∗ | 15.38±2.45∗∗ | 8.57 ± 2.37 | 0.002∗∗ | ||
| CREA | 0.69 ± 0.06 | 0.76 ± 2.07 | 0.80 ± 0.16 | 0.103 | ||
| Cystatin C | 31.01 ± 43.53 | 17.20 ± 7.06 | 59 ± 82.37 | 0.159 | ||
| GFR based on Cystatin | 3.25 ± 1.63 | 3.64 ± 1.64 | 1.87 ± 1.55 | 0.166 | ||
| 25 to 35 years old (n = 15) | GFR | 112.77 ± 15.02∗ | 97.93 ± 23.16∗ | 92.09 ± 5.15 | 0.038∗ | |
| BUN | 10.25 ± 2.22 | 15 ± 3.61 | 11 ± 3.30 | 0.213 | ||
| CREA | 0.78 ± 0.17 | 0.90 ± 0.10 | 0.94 ± 0.14 | 0.137 | ||
| Cystatin C | 41.35 ± 36.72 | 16.67 ± 3.03 | 24.54 ± 12.12 | 0.233 | ||
| GFR based on Cystatin | 1.76 ± 1.05 | 3.14 ± 0.39 | 2.39 ± 1.03 | 0.233 | ||
∗∗Kruskal-Wallis test; ∗ANOVA test; GFR: glomerular filtration rate; BUN: blood urea nitrogen; CREA: creatinine.