Table 5.

Comparison of urinary renal parameters in 3 age groups.

			Study group
			Deferoxamine	Deferasirox	Control
			Mean ± SD	Mean ± SD	Mean ± SD	p value
Age	Under 18 years old (n = 18)	U. NGAL	11.22 ± 17.98	13.02 ± 18.42	2.38 ± 0.46	0.331
		U. KIM-1	2.70 ± 97	3.52 ± 1.30	2.54 ± 0.94	0.247
		U. IL-18	79.42 ± 125.14	31.34 ± 44.47	20.69 ± 36.19	0.692
		U. CREA	89.50 ± 59.74	77.40 ± 42.01	—	0.786
		U. Alb	8.25 ± 17.15	1.13 ± 1.40	—	0.571
		U. NGAL/CREA	0.11 ± 0.10	0.19 ± 0.26	—	0.664
		U. IL-18/CREA	2.11 ± 3.26	0.63 ± 1.24	—	0.386
		U. KIM-1/CREA	0.04 ± 0.03	0.06 ± 0.05	—	0.386
		U. Alb/CREA	60.48 ± 98.93	14.35 ± 16.35	—	0.828
	18 to 25 years old (n = 27)	U. NGAL	6.80 ± 12.99	12.01 ± 20.77	12.75 ± 22.23	0.120
		U. KIM-1	3.14 ± 1.12	3.06 ± 1.34	3.69 ± 2.98	0.583
		U. IL-18	21.28 ± 52.53	71.66 ± 158.13	21.44 ± 25.20	0.608
		U. CREA	102.22 ± 66.48	101 ± 58.34	172.50 ± 85.56	0.343
		U. Alb	0.51 ± 0.38	1.85 ± 2.97	1.22 ± 0.62	0.451
		U. NGAL/CREA	0.08 ± 0.11	0.11 ± 0.11	0.03 ± 0.02	0.442
		U. IL-18/CREA	0.15 ± 0.26	0.71 ± 1.333	0.05 ± 0.05	0.884
		U. KIM-1/CREA	0.09 ± 0.16	0.03 ± 0.01	0.02 ± 0.01	0.338
		U. Alb/CREA	8 ± 9.70	14.92 ± 18.31	9.04 ± 8.05	0.962
	26 to 35 years old (n = 15)	U. NGAL	3.30 ± 0.77	6.84 ± 7.38	6.06 ± 6.66	0.845
		U. KIM-1	2.91 ± 0.88	3.52 ± 1.23	2.53 ± 0.66	0.307
		U. IL-18	6.48 ± 12.24	245.53 ± 406.78	10.01 ± 13.06	0.125
		U. CREA	81.75 ± 62.45	136.33 ± 168.26	203.67 ± 98	0.317
		U. Alb	0.43 ± 0.39	3 ± 3.59	1.11 ± 0.60	0.101
		U. NGAL/CREA	0.05 ± 0.03	0.07 ± 0.04	0.02 ± 0.001	0.050
		U. IL-18/CREA	0.04 ± 0.07	0.88 ± 1.12	0.05 ± 0.09	0.153
		U. KIM-1/CREA	0.05 ± 0.02	0.06 ± 0.04	0.01 ± 0.001	0.150
		U. Alb/CREA	5.20 ± 1.65	28.92 ± 25.88	7.40 ± 2.50	0.095

NGAL: neutrophil gelatinase-associated lipocalin; KIM-1: Kidney Injury Molecule-1; IL: interleukin; CREA: creatinine; Alb: albumin; U: urinary.