Figure 3.

Cross‐sectional amyloid beta effect on right uncinate fasciculus free water. Brain slices depict corresponding reconstructed white matter fiber using TRACULA. The bar chart on the left illustrates that participants that were Aβ +ve (red) had higher RUNC FW at baseline. Error bars represent ± 2 standard error. The scatterplot on the right illustrates that Aβ +ve participants (red) showed a higher FW than Aβ −ve participants (blue) across all positions in the RUNC, especially in the temporal part of the RUNC. Abbreviations: TRACULA, TRActs Constrained by UnderLying Anatomy; FW, free water; Aβ, amyloid beta; RUNC, right uncinate fasciculus