(A) Schematics of PDM’s charge-invertibility with pH change, the pKa of carboxylic acid and the pKa of the tertiary alkyl amine’s conjugated acid, respectively, coincide at around pH = 5.8. (B) Proposed schematics of charge-invertible micellization behavior. (C) Zeta-potential and (D) particle diameter measured from electrophoretic and dynamic light scattering, respectively, of 0.1 mg/mL PDM dissolved in 10mM sodium acetate buffer solution titrated from pH 5.1 to 6.8. (E) TEM images of PDM in aqueous solution at pH 5.1 and 6.5, respectively. Scale bar 200 nm.