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. Author manuscript; available in PMC: 2020 Mar 1.
Published in final edited form as: J Steroid Biochem Mol Biol. 2018 Nov 30;187:166–173. doi: 10.1016/j.jsbmb.2018.11.015

Figure 7. TXNIP and P-JNK protein association with ASK1 increases in the ECD phase.

Figure 7.

Co-IPs of ASK1 in both (A) HL60 and (B) U937 cells followed by determination of proteins in the complex by Western blotting with different antibodies. This showed that in addition to TXNIP and MKK4, P-JNK1 and P-p38 also bind to ASK1 in all treatment groups, and their levels are markedly increased in the ECD phase (lanes 4 and 8). Note the absence of JNK2 binding to ASK1, and the specificity of the Co-IP is also shown by the lack CRK-L binding to ASK1. ftable