Table 1.

The role of MV in the tumor.

Main role	MV origins	Acting cells	Type of action
Promote tumor progression
Promote growth	Glioblastoma cells	Human glioma cells	MVs transport RNA and proteins
Promote tumor angiogenesis	Human lung cancer cells	Stromal cells	Express more angiogenic factors
Mediated immune escape	Human colorectal cancer cells	NK cells	MVs transport miR-126 and TGF-β
	Melanoma cells	T cells	MVs transport FasL
Promote thrombosis	Human pancreatic cancer cells	Platelets	MVs transport tissue factor
Promoting normal cell apoptosis	Lung and pancreatic tumor cells	Myoblasts	MVs transport miR-21
Inhibited tumor progression
Induce tumor cell apoptosis	Platelets	Lung and colon carcinoma ectopic tumors	MVs transport miR-24
	Human hepatic stem cells	Hepatoma cells	MVs transfer miRNAs with potential antitumor activity