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Expression of DNA methyltransferases in melasma patients. Relative expression of DNMT1 (a) and DNMT3b (b) mRNAs in skin biopsies of unaffected and melasma skin by RT-qPCR. The results were normalized with respect to 18s gen. The results correspond to the mean ± SD of 30 patients at basal conditions. ∗ Significant differences with p<0.05 (P values for t-test).
