Table 1.
Demographics of 92 patients with Candida auris
| Category | Total n = 92 (100%) |
|---|---|
| Male | 48 (52.2%) |
| Age group | |
| 16–35 years | 20 (21.7%) |
| 36–55 years | 26 (28.3%) |
| 56–75 years | 30 (32.6%) |
| 76–96 years | 16 (17.4%) |
| Location in hospital | |
| ICU | 30 (32.6%) |
| Special care | 30 (32.6%) |
| Ward | 27 (29.3%) |
| Outpatient | 5 (5.4%) |
| Diabetes mellitus | 26 (28.3%) |
| Malignancy | 17 (18.5%) |
| Surgery | 53 (57.6%) |
| Abdominal | 12 (13%) |
| Cardiothoracic | 8 (8.7%) |
| Neurosurgery | 14 (15.2%) |
| ENT | 9 (9.8%) |
| Orthopedics | 7 (7.6%) |
| Others | 2 (2.17%) |
| ICU stay in last 30 days | 41 (44.6%) |
| Last ICU stay duration (weeks) ≤ 2 Weeks | 31 (75.6%) |
| HDU stay in last 30 days | 62 (67.4%) |
| Last HDU stay duration (weeks) | |
| ≤ 2 Weeks | 52 (56.5%) |
| Indwelling lines | 81 (88.04%) |
| Antibiotics in last 90 days | 88 (95.6%) |
| Antifungals in last 90 days | 36 (39.1%) |
| Fluconazole | 19 (20.7%) |
| Voriconazole | 3 (3.3%) |
| Amphotericin | 7 (7.6%) |
| > 1 Antifungal | 7 (7.6%) |
| Prior antifungal duration (weeks) | |
| ≤ 2 Weeks | 25 (27.2%) |
| Isolation of multi-drug resistant bacteria | |
| Prior toC.auris (≤ 90 days) | 48 (52.2%) |
| Coinfection with C.auris | 29 (31.5%) |
| Infected cases | 65 (70.7%) |
| Candidemia | 38 (58.5%) |
| Non-candidemia | 27 (41.5%) |
| UTI | 19 |
| Peritonitis | 3 |
| Nosocomial ventriculitis | 1 |
| Empyema | 1 |
| Surgical Site Infection | 1 |
| Otitis externa | 1 |
| Keratitis | 1 |
| Colonized cases | 27 (29.3%) |
| Asymptomatic candiduria | 21 |
| Central line tip | 4 |
| Ear Swab | 1 |
| Oral Swab | 1 |
| Antifungal resistance (n = 63) | |
| Fluconazole | 63 (100%) |
| Voriconazole | 18 (28.57%) |
| Amphotericin | 5 (7.93%) |
| Mean hospital stay (days) | 30.73 |
| Median hospital stay (days) | 25 (1–163) |
| Mortality | 39 (42.4%) |
| C auris death | 19 (48.7%) |
| 14-day mortality | 29 (31.5%) |
| Mean days in which mortality occurred (days) | 12.41 |
| Median days in which mortality occurred (days) | 7 (1–69) |
| Clinical failure | 38 (41.3%) |
| Microbiological failure (Candidemia) | 11 (40.74%) |