Figure 2.

Cut-through of the three-dimensional finite-element mesh used to discretize the tumour and the host tissue (volume of analysed domain = 1.2 cm³). The solid red lines depict the idealized vascular network used in the simulations (black dots correspond to the vascular nodes) which is relatively evenly distributed in three-dimensional space. Note that the two model discretizations are non-conforming. On the right, the colouring of the hexahedral elements demonstrates the visible partitions of the mesh, as decomposed for the purposes of the scalable in silico executions. (Online version in colour.)