Figure 12.

Schematics of the procedure to test whether the improved MAPE values obtained excluding a localized group of residues from removal do not depend on their location. As described in figure 11, the 20 residues to remove can be randomly selected only outside of a sphere of 1 nm radius. The centre of the sphere, however, cannot be localized closer than 2 nm to the point employed for the previous analysis, namely the molecule’s sequence centre (i.e. the mechanical hinge). Ten different positions for the sphere are randomly identified, and for each of them, 10 different models where 20 residues have been randomly removed have been constructed. (Online version in colour.)