Table 2.
Univariate analysis of survival after recurrence
| Variable | Median SAR (months) | p-value | |
|---|---|---|---|
| Age | < 65 years | 36.7 (26.0–47.3) | 0.71 |
| ≥65 years | 45.6 (29.4–61.8) | ||
| Sex | Male | 37.8 (33.6–42.1) | 0.49 |
| Female | 55.4 (0.0–110.8) | ||
| Location | Proximal | 37.8 (13.9–61.8) | 0.82 |
| Distal | 38.7 (27.9–49.4) | ||
| Time to recurrence | < 1 year | 31.7 (5.9–57.6) | 0.16 |
| ≥1 year | 44.4 (31.4–57.4) | ||
| Stage | II, high risk | 49.7 (N/A) | 0.36 |
| III | 37.8 (30.2–45.5) | ||
| T-stage | T1–3 | 38.2 (29.0–47.4) | 0.31 |
| T4 | 28.1 (0.0–64.8) | ||
| N-stage | N0–1 | 49.7 (26.1–73.3) | 0.064 |
| N2 | 29.3 (11.4–47.3) | ||
| Histology | Non-MAC | 44.4 (31.2–54.7) | 0.003 |
| MAC | 20.0 (4.9–35.0) | ||
| Curative resection after distant recurrence | Not done | 23.6 (12.1–35.2) | < 0.001 |
| Done | Not reached | ||
| MSI | MSS/MSI-L | 38.2 (28.2–48.2) | 0.35 |
| MSI-H | 9.3 (1.7–38.2) |
Abbreviations: MAC mucinous adenocarcinoma, MSS microsatellite stable, MSI-L microsatellite instability-low, MSI-H microsatellite instability-high, N/A not available