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. 2019 Apr 21;2019:8526083. doi: 10.1155/2019/8526083

Figure 6.

Figure 6

(a–d) Immunohistochemical analysis of the lung tissue sections for the detection of nuclear factor erythroid-derived 2-like 2 (Nrf2) in mice, at the end of the one-month exposure period to either air (control) or waterpipe smoke (WPS) with or without gum Arabic (GA) administration (15% w/v in drinking water). (a) Representative section of the lung of air-exposed mice showing focal mild nuclear expression of Nrf2 by bronchial epithelium (arrow). (b) Representative section of the lung of the GA + air group displaying nuclear expression of Nrf2 by bronchial epithelium (arrow). (c) Representative section of the lung of WPS-exposed mice showing nuclear expression of Nrf2 by bronchial epithelium (arrow). (d) Representative section of the lung of GA + WPS-exposed mice displaying substantially more nuclear expression of Nrf2 by bronchial epithelium (arrow) and alveolar cells (arrowhead).