Table 2.
Coronary microvascular dysfunction pathways | Microvascular dysfunction | Macrovascular dysfunction |
---|---|---|
Non-endothelial dependent |
aCoronary flow reserve in response to adenosine 2.8 (normal ≥ 2.5) |
bChange in coronary diameter in response to nitroglycerin 0% (normal ≥ 20%) |
Endothelial dependent |
cChange in coronary blood flow in response to acetylcholine 48% (normal ≥ 50%) |
dChange in coronary diameter in response to acetylcholine − 6% (normal ≥ 5%) |
a Non-endothelial-dependent microvascular dysfunction with coronary flow reserve 2.8 (adenosine). b Non-endothelial-dependent macrovascular dysfunction with 0% (nitroglycerin) coronary diameter change. c Endothelial-dependent microvascular dysfunction with coronary blood flow change 48%. d Endothelial-dependent macrovascular dysfunction with coronary diameter change − 6% in response to acetylcholine