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DNA fragmentation induced by the hypoglycemic coma is exacerbated by RH. The presence of DNA fragmentation was examined by the TUNEL assay and Hoechst was used as counterstain. (a) Representative micrographs showing TUNEL-positive cells in CA1 and the DG of rats treated with RH/SH. (b) In rats exposed to SH alone TUNEL-positive were detected only in the crest of the DG.
