TABLE III.
Physical Examination Results*
| Age 0–5 years, n = 34 (%) | Age 6–12 years, n = 18 (%) | Age 13 years +, n = 22 (%) | Total, n = 74 (%) | |
|---|---|---|---|---|
| Median height (Z-score) | 0.30 | 1.10 | 1.08 | 0.72 |
| Height range (Z-score) | −2.6 to 2.0 | −0.62 to 2.26 | −2.95 to 2.73 | −2.95 to 2.73 |
| Median weight (Z-score) | 0.13 | 0.09 | 0.73 | 0.42 |
| Weight range (Z-score) | −1.81 to 2.44 | −1.63 to 1.57 | −1.52 to 2.60 | −1.81 to 2.60 |
| Body mass index (Z-score) | 0.25 | −0.18 | 0.33 | 0.09 |
| Body mass index range (Z-score) | −2.18 to 2.20 | −2.25 to 0.84 | −2.58 to 2.31 | −2.58 to 2.31 |
| Median head circumference (Z-score) | 0.19 | −0.22 | 0.54 | 0.21 |
| Head circumference range | −1.76 to 2.78 | −1.47 to 1.25 | −2.1 to 3.20 | −2.16 to 3.20 |
| Facial asymmetry | 1/32 (3.1) | 1/17 (5.9) | 4/22 (18.2) | 6/71 (8.5) |
| Epicanthal folds | 23/32 (71.8) | 3/17 (17.6) | 5/22 (22.7) | 31/71 (43.7) |
| Hypertelorism | 21/32 (65.6) | 4/17 (23.5) | 12/22 (54.5) | 37/71 (43.7) |
| Upslanting palpebral fissures | 5/32 (15.6) | 4/17 (23.5) | 2/22 (9.1) | 11/71 (15.5) |
| High arch palate | 2/32 (6.3) | 2/17 (11.8) | 2/22 (9.1) | 6/71 (8.5) |
| Poor dentitiona | 5/32 (15.6) | 4/17 (23.5) | 8/22 (36.4) | 17/71 (23.9) |
| 5th digit clinodactyly | 12/33 (36.3) | 6/17 (35.3) | 8/22 (36.4) | 26/72 (36.1) |
| Pes planus | 16/32 (50.0) | 5/16 (31.3) | 5/22 (22.7) | 26/71 (36.6) |
| Ankle pronation | 8/32 (25.0) | 1/17 (5.9) | 2/22 (9.1) | 11/71 (15.5) |
| Scoliosis or Kyphosis | 7/22 (31.8) | |||
| Hypotonia | 22/33 (66.7) | 7/17 (41.2) | 7/22 (31.8) | 36/72 (50.0) |
| Tremorb | 3/33 (9.1) | 5/17 (29.4) | 9/22 (40.9) | 17/72 (23.6) |
*
Number of subjects at top of column unless otherwise noted.
a
Poor dentition classified as four or more caries/fillings, significant malocclusion, current or previous orthodontia, or edentulous.
b
Tremor included intention and/or postural tremor.