Table 3.

Stability evaluation for antiepileptic drugs (AEDs).

	QC level	RT, 24 h (% DIF)	Freeze-thaw (% DIF)	Long term, 32 days (% DIF)	15 °C for 24 h (% DIF)
GBP	LLOQ	−0.440	1.28	−1.35	0.850
	Low	7.44	−1.25	−6.45	4.06
	Mid	1.74	13.9	−2.43	0.400
	High	2.32	9.77	−8.67	7.32
LTG	LLOQ	−11.1	4.86	11.9	8.17
	Low	−3.63	2.03	2.28	−2.90
	Mid	9.37	9.07	10.4	−0.300
	High	−1.13	9.24	8.96	0.390
LEV	LLOQ	1.58	−9.68	−14.1	−3.23
	Low	6.48	−0.920	−7.39	−2.89
	Mid	−0.130	10.6	0.410	−1.68
	High	2.09	11.8	−0.630	−4.05
MHD	LLOQ	−7.98	−1.89	−1.91	−1.26
	Low	0.460	2.96	−3.04	0.000
	Mid	2.26	15.3*	2.42	0.910
	High	−0.610	11.6	−0.140	2.32
ZNS	LLOQ	−18.7*	−10.23	0.900	−5.60
	Low	3.84	−0.420	−8.59	−0.070
	Mid	2.52	16.3*	−2.09	0.330
	High	1.66	15.3*	−1.97	5.10

^*Did not meet stability criteria