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. Author manuscript; available in PMC: 2019 May 6.
Published in final edited form as: Science. 2009 Mar 12;324(5927):654–657. doi: 10.1126/science.1170803

Figure 2. The circadian clock controls Nampt gene expression.

Figure 2

(A) Scheme of the NAD+ salvage pathway in mammals. NAM, nicotinamide; NMN, nicotinamide mononucleotide; NAMPT, nicotinamide phosphoribosyltransferase; NMNAT1-3, nicotinamide mononucleotide adenyltransferase. (B) Nampt gene expression in livers from light-entrained wt and c/c mutant mice was quantified by q-PCR. Nampt gene expression at ZT 15 in liver from wt mice was set to 1. (C) Nampt and Dbp gene expressions in serum-entrained MEFs from wt and c/c mutant mice were quantified by q-PCR. Expression at time 0 in wt MEFs was set to 1. All data are means ± SEM of three independent samples.