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. Author manuscript; available in PMC: 2020 May 1.
Published in final edited form as: JACC Heart Fail. 2019 May;7(5):383–391. doi: 10.1016/j.jchf.2019.01.007

Central Illustration: Positive Sodium Balance with Net Fluid Loss Still Portends Worse Survival.

Central Illustration:

Urine sodium excretion, as metric of diuretic response, carries prognostic value. A considerable percentage (29%) of participants excreted less sodium than would be consumed in their diet (positive sodium balance), and these patients experienced decreased six-month survival (log rank p = 0.03). Even those who exhibited positive sodium balance and net fluid loss (23%) still experienced decreased survival (log rank p = 0.01).