KEY RESOURCES TABLE

REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
Mouse monoclonal anti-β-Actin antibody	Sigma-Aldrich	Cat# A2228
Rabbit polyclonal anti-KRAS antibody	Proteintech	Cat# 12063-1-AP
Rabbit monoclonal anti-KRAS (G12V specific) antibody	Cell signaling	Cat# 14412S
Human TNFα neutralization mouse monoclonal antibody	R&D Systems	Cat# MAB201-100
Human IFNγ neutralization mouse monoclonal antibody	Thermo Fisher	Cat# 14-7318-81
Mouse IgG1 isotype control	Thermo Fisher	Cat# 02-6100
CD3 monoclonal antibody (OKT3)	Thermo Fisher	Cat# 16-0037-81
Chemicals, Peptides, and Recombinant Proteins
Human recombinant IL-2	PeproTech	Cat# 200-02
Birinapant	Selleckchem	Cat# S7015
BV-6	Selleckchem	Cat# S7597
GDC0152	Selleckchem	Cat# S7010
AZD5582	Selleckchem	Cat# S7362
LCL161	Selleckchem	Cat# S7009
AT406	Selleckchem	Cat# S2754
EEBL	Emory ECBDC	N/A
Batimastat	Selleckchem	Cat# S7155
Critical Commercial Assays
CellTiter-Blue® Cell Viability Assay	Promega	Cat# G8081
TNFα Human ELISA Kit	Thermo Fisher	Cat# KHC3011
IFNγ Human ELISA Kit	Thermo Fisher	Cat# EHIFNG
Experimental Models: Cell Lines
Human KRAS (G12V/+) SW48 Cell Lines	Horizon Discovery	Cat# HD 103-007
Human KRAS (G12V/+) LIM1215 Cell Lines	Horizon Discovery	Cat# HD 116-006
Human KRAS (G12V/+9n) NCI-H838 Cell Line	Horizon Discovery	Cat# HD 114-003
Caco-2	ATCC	Cat# HTB-37
SW403	ATCC	Cat# CCL-230
SW480	ATCC	Cat# CCL-228
SW620	ATCC	Cat# CCL-227
Peripheral Blood Mononuclear Cells, Human, Normal	ATCC	Cat# PCS-800-011
Software and Algorithms
Graphpad Prism	Graphpad; v7	https://www.graphpad.com/scientific-software/prism/
IncuCyte S3 software	Essen BioScience; S3	https://www.essenbioscience.com/en/products/software/incucyte-s3-software-v2018b/
Final Cut Pro X	Apple	https://www.apple.com/final-cut-pro/
Other
Dynabeads™ CD3	Thermo Fisher	Cat# 11151D
MagniSort™ Human CD56 Positive Selection Kit	Thermo Fisher	Cat# 8802-6835-74
Dynabeads™ CD19 Pan B	Thermo Fisher	Cat# 11143D