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. Author manuscript; available in PMC: 2020 Mar 26.
Published in final edited form as: Angew Chem Int Ed Engl. 2019 Feb 27;58(14):4705–4709. doi: 10.1002/anie.201900545

Table 5.

Hydroacylation Scope with α-Aryl Aldehydes[a]

graphic file with name nihms-1018968-t0012.jpg
[a]

With 0.10 mmol of 5.

1H NMR yields of 6 are given in parentheses. Isolated yields over two steps are given of 7. Diastereoselectivities of each step were determined by 1H NMR analysis of the unpurified reaction mixture. Enantioselectivities (ee’s) were determined by chiral SFC analysis.