Table 1.
Frequencies of Coding Variants as a Function of Variant Frequency.
| Common Variantsa (%; 95% bootstrap CIb) | Strain Private Variants (%; 95% bootstrap CIb) | |
|---|---|---|
| Coding variants | 75,509 (NA) | 439 (NA) |
| Synonymous variants | 49,964 (66.2; 65.8–66.5) | 129 (29.4; 25.1–33.7) |
| Missense variants | 25,303 (33.5; 33.1–33.8) | 295 (67.2; 62.4–71.4) |
| Nonsense variants | 242 (0.32; 0.28–0.36) | 15 (3.4; 1.9–5.3) |
a
Common variants are defined as variants present in two or more laboratory strains, including the C57BL/6J reference.
b
95% confidence intervals are derived from 1,000 bootstrap resamples of observed variants.