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. 2019 May 5;9(5):e025567. doi: 10.1136/bmjopen-2018-025567

Table 1.

Characteristics of patients admitted to hospital for accidental opioid overdose, 2006–2015

Characteristic Admission
n (%)
Readmission
n (%)
Hospitalisations 2433 121
Type of opioid overdose
 Opium 8 (0.3) 0
 Heroin 419 (17.2) 15 (12.4)
 Methadone 401 (16.5) 26 (21.5)
 Synthetic opioids* 123 (5.1) 7 (5.8)
 Other opioids† 1101 (45.3) 46 (38.0)
 Unspecified/other opioids 515 (21.2) 34 (28.1)
Sex
 Female 1134 (46.6) 54 (44.6)
 Male 1299 (53.4) 67 (55.4)
Age (years)
 <10 36 (1.5) 0
 10–19 80 (3.3) <5
 20–29 371 (15.2) 16 (13.2)
 30–39 411 (16.9) 19 (15.7)
 40–49 415 (17.1) 15 (12.4)
 50–59 477 (19.6) 21 (17.4)
 60–69 329 (13.5) 36 (29.8)
 70–79 186 (7.6) 10 (8.3)
 ≥80 128 (5.3) <5
Low income 719 (29.6) 35 (28.9)
Rural residence 325 (13.4) 17 (14.1)
Substance use disorders
 Opioids 192 (7.9) 25 (20.7)
 Sedatives and hypnotics 22 (0.9) <5
 Stimulants 112 (4.6) 9 (7.4)
 Other 395 (16.2) 35 (28.9)
Romano comorbidity score
 0 1380 (56.7) 54 (44.6)
 1–2 723 (29.7) 40 (33.1)
 ≥3 330 (13.6) 27 (22.3)
Other medical history
 Psychiatric illness 931 (38.3) 58 (47.9)
 Pneumonia 224 (9.2) 27 (22.3)
 Other respiratory illness 473 (19.4) 35 (28.9)
 HIV 42 (1.7) <5
 Hepatitis C 33 (1.4) <5
 Cancer 172 (7.1) 11 (9.1)
Opioid prescription history§
 Methadone 29 (1.2) <5
 Buprenorphine/naloxone 30 (1.2) <5
 High-dose opioid for pain 569 (23.4) 33 (27.3)
 No use of opioids for pain 1097 (45.1) 50 (41.3)
Other prescription history§
 Sedatives and hypnotics 571 (23.5) 37 (30.6)
 Stimulants 63 (2.6) <5

Types of opioid overdose correspond to ICD-10 T40.0-T40.4 and T40.6 (some overdoses appear in >1 category). Readmissions are defined as additional accidental opioid overdose admissions within 365 days of prior admission.

*Includes buprenorphine, fentanyl, pethidine and tramadol.

†Includes codeine, hydromorphone, morphine and oxycodone.

‡Based on diagnoses at a physician or hospital visit in the 365 days before opioid overdose.

§Based on dispensings in the 180 days prior to opioid overdose. High-dose opioid use is defined by a dispensing of opioid pain medication of >90 oral morphine equivalents per day. Small cell sizes are denoted as '<5' or 0 as applicable.