Table 2.
Demographic features of F3 and F4 patients, treated for 12 weeks, from the Integrated analysis (ASTRAL and Polaris studies)
| F3 | F4 | ||
| Total n of patients | 236 | 444 | |
| Mean age, y (range) | 57 (33-81) | 58 (34-82) | |
| Male, n (%) | 162 (69) | 355 (80) | |
| Mean BMI, kg/m2 (range) | 28 (18-57) | 28 (17-47) | |
| HCV GT, n (%) | 1a | 67 (28) | 107 (24) |
| 1b | 26 (11) | 48 (11) | |
| 2 | 34 (14) | 58 (37) | |
| 3 | 77 (33) | 164 (37) | |
| 4 | 21 (9) | 49 (11) | |
| 5 | 5 (2) | 5 (1) | |
| 6 | 6 (3) | 13 (3) | |
| Baseline HCV RNA log10 IU/mL, mean (range) | 6.3 (4.0-7.4) | 6.2 (4.1-7.5) | |
| Treatment Experienced, n (%) | 66 (28) | 176 (40) |
Legend: BMI: Body Mass Index; GT: genotype; IU: International Units