Table 1.
Previous reported cases in literature
Patient, Year | Gestation Days | Day 0 Bhcg | U/B | Crl Diameter-mm | MTX -TR | DOF | Simptoms | Blood-loss | Bhcg (before surgery) | Result |
1, 1993 | 77 | 3640 | U | 25 × 30; Crl 11 and 13 | 31.5 mg of MTX Into Each Gestational Sac; 2 Days Later a Systemic Dose Of 63 Mg (IM) | 31 | - | S | ||
2, 1997 | Unsure | 539 | B | Diameter 25 | Single Dose 50 Mg/M2) | 4 | Acute Abdomen | 100 | U | |
3, 2008 | Non Reported | 763 | U | Not Reported | Multiple Dose Regimen (1 Mg/Kg on Days 1,3,4 and 7 + 0.1 Mg/Kh of Folinic Acid on Days 2,4,6 and 8) + a Single Dose on Day 14 Th (1 Mg/Kg) | 32 | - | S | ||
4, 2009 | 49 | 18780 | U | CRL 11 Ans 8 Mm | Single Dose (1 Mg/Kg) | 42 | - | S | ||
Ours, 2016 | 44 | 13217 | U | 5 and 16 | Multiple Dose (50 Mg/Mg) on Day 1, 7 and 14 + Folic Rescue (5 Mg/Die Per Os) | 18 | Acute Abdomen | 2500 | 3659 | U |
CRL: Crown-rump length; DOF: Duration of follow-up; U/B: Unilateral/Bilateral; U/S: Success/unsuccess; MTX-TR: Methotrexate Treatment Regimen