Table 2.

FEV₁ percentages and demographic features of the patients as to COPD stages and laboratory data

	Stage I (n=9, 3.7%)	Stage II (n=57, 23.5%)	Stage III (n=117, 48.1%)	Stage IV (n=60, 24.7%)	P
Age (Year)	64.78±12.48	65.32±13.89	70.93±10.35	66.97±10.17	0.007*
Gender					0.241**
Female	3 (33.3%)	22 (38.6%)	42 (35.9%)	16 (26.7%)
Male	6 (66.7%)	35 (61.4%)	75 (64.1%)	44 (73.3%)
Length (m)	1.61±0.13	1.58±0.15	1.60±0.16	1.65±0.12	0.062*
Kilo (kg)	73.78±13.25	73.40±19.73	72.12±18.68	68.08±16.95	0.371*
BMI(kg/m2)	29.11±7.62	29.85±9.65	29.13±11.92	25.43±6.99	0.048*
Levels of AAT	193.89±45.95	199.44±59.29	211.01±63.16	212.22±51.26	<0.001*
Negatif	-	-	1 (0.9%)	-	0.097**
Reference range	3 (33.3%)	22 (38.6%)	31 (26.5%)	14 (23.3%)
Positive	6 (66.7%)	35 (61.4%)	85 (72.6%)	46 (76.7%)
Exposure to tobacco					0.660**
Yes	6 (66.7%)	27 (47.4%)	58 (49.6%)	34 (56.7%)
No	3 (33.3%)	30 (52.6%)	59 (50.4%)	26 (43.3%)
WBC	7.89±1.42	10.47±4.88	10.38±5.15	10.69±4.11	0.245*
CRP	1.61±1.17	3.70±4.13	5.49±7.12	5.22±6.61	0.179*
pH	7.43±0.08	7.42±0.06	7.42±0.08	7.40±0.11	0.419*
pCO2	41.22±8.39	41.06±9.47	43.25±11.48	47.54±12.29	0.056*
pO2	46.67±12.12	49.56±14.77	46.09±11.39	43.10±13.44	0.194*
Number of hospitalization in	1±0.87	1.84±1.66	2.52±2.42	2 (0-15%)	0.024*
a year, median
Exitus in hospital					0.049**
Yes	-	1 (1.8%)	3 (2.6%)	5 (%)
No	9 (100%)	56 (98.2%)	113 (97.4%)	54 (91.5%)
Exitus in the first one year					0.193**
Yes	2 (22.2%)	7 (12.3%)	35 (23.7%)	14 (23.7%)
No	7 (77.8%)	50 (87.7%)	81 (69.8%)	45 (76.3%)
Hospitalization to intensive					0.008**
unit care in the first one year
Yes	-	5 (8.8%)	24 (20.7%)	15 (25.0%)
No	9 (100%)	52 (91.2%)	92 (79.3%)	45 (75.0%)

* Kruskall-Wallis test; **Ki-kare test