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Chromosome 4 off target site genotype distribution in live offspring from intercrosses between G1 animals heterozygous for the on and off target site.
| Genotype | No. observed | No. expected* | Test score (χ2, P value)† |
|---|---|---|---|
| Wild-type | 4 | 4.25 | 0.06, NS |
| Heterozygous | 9 | 8.5 | |
| Homozygous | 4 | 4.25 |
Assumes a 1:2:1 segregation ratio of the off target site amongst live offspring (N=17 total; N=4 Gm26878+/+, N=10 Gm26878+/−, N=3 Gm26878−/−).
NS, not significant
