Table 1. Baseline characteristics of study participants.
| Total study population n = 158 |
|
|---|---|
| Patient age (median, IQR) | 37 (31–43) |
| Patient sex (% male) | 102 (64·6) |
| TB Class | |
| Pulmonary | 132 (83·5) |
| Extra-pulmonary | 26 (16·5) |
| TB Category * | |
| Relapse | 62 (39·2) |
| TALTF | 7 (4·4) |
| Fail | 5 (3·2) |
| Other | 84 (53·2) |
| No. of previous TB episodes | |
| 1 | 138 (87·3) |
| 2 | 17 (10·8) |
| >2 | 3 (1·9) |
| HIV status | |
| Negative | 27 (17·1) |
| Positive | 131 (82·9) |
| CD 4 count (median, IQR) | 171 (61–324) |
| ART failure (n = 64) | 24 (37·5) |
| Karnofsky score at baseline (median, IQR) | 90 (80–100) |
| HR >100bpm | 95 (60·1) |
| RR>20bpm | 37 (23·4) |
| SBP<100mmHg | 50 (31·7) |
| BMI | |
| ≥18.5 | 36 (23·7) |
| 16–18.4 | 75 (49·3) |
| <16 | 41 (27·0) |
| Anaemia | 34 (22·2) |
| Diabetes | 5 (3·3) |
| Renal impairment | 52 (33·8) |
| Chronic Lung disease on CT Thorax (n = 102) | 90 (88·2) |
| Pulmonary function testing (n = 103) | |
| Normal | 34 (33·0) |
| Obstructive | 6 (5·8) |
| Restrictive | 62 (61·2) |
| Smoker | |
| Never | 116 (73·4) |
| Former | 41 (26·0) |
| Current | 1 (0·6) |
| History of alcohol excess | 27 (17·1) |
* Relapse = a patient previously treated for TB, declared cured or treatment completed, who is diagnosed again with smear or culture positive TB; Treatment after failure = a patient who is started on retreatment regimen after having failed previous treatment; Treatment after loss to follow up (TALTF) = a patients who returns to treatment, positive bacteriologically, following interruption of treatment for 2 or more consecutive months; Other previously treated = all previously treated cases that do not fit any of the above definitions http://www.who.int/tb/err/rr_final_forms_en.pdf.