Table 2. Features associated with clinical outcome on TB retreatment.
| Successful outcome n (%) |
p-value | OR (95% CI) | p-value | aOR (95% CI)* | |
|---|---|---|---|---|---|
| Confirmed TB | |||||
| No | 47/66 (71.2 | 0.51 | 0.80 (0.40–1.58) | 0.55 | 0.80 (0.37–1.70) |
| Yes | 61/92 (66.3) | ||||
| TB si | |||||
| Pulmonary | 93/132 (70.5) | 0.20 | 0.57 (0.23–1.36) | - | - |
| Extra-pulmonary | 15/26 (57.7) | ||||
| TB Category | |||||
| Relapse | 47/63 (74.6) | ||||
| TLTFU | 5/7 (71.4) | 0.86 | 0.85 (0.15–4.83) | - | - |
| Fail | 3/5 (60.0) | 0.48 | 0.51 (0.08–3.34) | - | - |
| Other | 53/83 (63.9) | 0.17 | 0.60 (0.29–1.24) | - | - |
| Age | |||||
| <3 | 22/32 (68.8) | ||||
| 30–35 | 28/43 (65.1) | 0.74 | 0.85 (0.32–2.25) | 0.92 | 1.06 (0.36–3.11) |
| 36–4 | 39/56 (69.6) | 0.93 | 1.04 (0.41–2.67) | 0.74 | 1.20 (0.40–3.57) |
| >45 | 19/27 (70.4) | 0.89 | 1.08 (0.35–3.29) | 0.85 | 1.12 (0.34–3.66) |
| Gender | |||||
| Female | 34/56 (60.7) | 0.13 | 1.71 (0.86–3.41) | 0.32 | 1.48 (0.69–3.20) |
| Male | 74/102 (72.6) | ||||
| HIV status | |||||
| Negative | 21/27 (77.8) | 0.25 | 0.56 (0.21–1.50) | 0.60 | 0.74 (0.24–2.30) |
| Positive | 87/131 (66.4) | ||||
| HR >100bp | |||||
| No | 47/63 (74.6) | 0.17 | 0.61 (0.30–1.24) | - | - |
| Yes | 61/95 (64.2) | ||||
| RR>20bpm No Yes |
64/95 (67.4) 44/63 (69.8) |
0.74 |
- 1.12 (0.56–2.23) |
- |
- |
| SBP<100mmHg | |||||
| No | 82/108 (95.9 | 0.003 | 0.34 (0.17–0.70) | 0.02 | 0.41 (0.19–0.87) |
| Yes | 26/50 (52.0) | ||||
| BMI | |||||
| ≥18.5 | 23/36 (63.9) | ||||
| 16–18.4 | 58/75 (77.3) | 0.14 | 1.93 (0.81–4.60) | - | - |
| <16 | 24/41 (58.5) | 0.63 | 0.80 (0.32–2.00) | - | - |
| Anaemia | |||||
| No | 88/119 (74.0) | 0.02 | 0.40 (0.18–0.87) | 0.11 | 0.50 (0.2.17) |
| Yes | 18/34 (52.9) | ||||
| Chronic Lung Disease on CT | |||||
| No | 11/12 (91.7) | 0.32 | 0.34 (0.04–2.80) | - | - |
| Yes | 71/90 (78.9) | ||||
| Abnormal Spirometry | |||||
| No | 32/34 (94.1) | 0.10 | 0.30 (0.06–1.27) | - | - |
| Yes | 56/69 (81.2) | ||||
| Diabetes | |||||
| No | 101/146 (69.2) | 0.61 | 1.78 (0.19–16.4) | - | - |
| Yes | 4/5 (80.0) | ||||
| Renal impairment | |||||
| No | 74/102 (72.5) | 0.11 | 0.56 (0.28–1.13) | - | |
| Yes | 31/52 (59.6) |
* adjusted for age, gender, HIV, confirmed TB, hypotension, anaemia