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Effect of repetitive stimulation on PLD1(K898R)-induced blockage of ACh release. (A) Trains of stimuli (50 Hz, 1 sec) were elicited before (control) and at the indicated times after presynaptic injection of PLD1(K898R), and postsynaptic responses were recorded. (B) For comparison, the responses to 50-Hz trains before (thin line) and 120 min after PLD1(K898R) injection (thick line) were scaled at the first response of the train.
