Table 1. Summary of experimental results taken from Edelmann et al.[11].
| Property | 1:1 t-LTP | 1:2 t-LTP | 1:4 t-LTP |
|---|---|---|---|
| Location of t-LTP expression | Pre | Mixed | Post* |
| Location of t-LTP induction | Post | Post | Post |
| Number of repeated stimuli | 70–100 | 50 | 25–35 |
| Stimulus repetition frequency¶ | 0.5 Hz | 0.5 Hz | 0.5 Hz |
| Test frequency§ | 0.05 Hz | 0.05 Hz | 0.05 Hz |
| NMDA receptor-dependent | Yes | Yes | Yes |
| BDNF-dependent | No | Partial | Yes |
| Slow expression (30 min) | Yes | Yes | Yes |
| t-LTP Occlusion by 1:1 protocol | -- | n.d. | No |
n.d. = data not available.
* The paired pulse ratio (PPR) change induced by the 1:4 t-LTP protocol was small and not significant, but the PPR change distribution reveals occasional contamination by presynaptic expression.
¶ This frequency was used during t-LTP induction, each stimulus elicited either 1 EPSP paired with 1 bAP or 1 EPSP paired with 4 bAPs.
§ This frequency was used during the phase of t-LTP expression, each stimulus elicited a single EPSP.