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. 2019 Apr 24;13(4):e0007264. doi: 10.1371/journal.pntd.0007264

Fig 6. Deglutamylase genes are overexpressed during L. major autophagy.

Fig 6

(A) RT-qPCR quantification of kmp11 (Kinetoplastid Membrane Protein, used as a control), ccp5a and ccp5b mRNA expression, after culture of WT cells in a serum-deprived medium (means ± sd from a minimum of three independent experiments). We noted overexpression of ccp5a and ccp5b when cells were cultivated in a serum-deprived medium. (B) Growth curve of WT, CCP5A and CCP5B overexpressing cells cultivated in a serum-deprived medium (means from a minimum of three independent experiments). Significant growth defects could be observed in starvation conditions when CCP5A or CCP5B when overexpressed. Student t-test: *: p<0.05, **: p<0.01, ***: p<0.001.