Skip to main content
. 2019 Jan 23;21(5):648–658. doi: 10.1093/neuonc/noz024

Table 3.

Overall concordance rates for the changes of RANO single items upon assessment of newly diagnosed LM between first evaluation and baseline evaluated using ICC

MRI Findings All Raters (NO + NR) (n = 19) NO (n = 10) NR (n = 9)
Alpha Lower Limit 95% CI Upper Limit 95% CI Alpha Lower Limit 95% CI Upper Limit 95% CI Alpha Lower Limit 95% CI Upper Limit 95% CI
Brain
Nodules (subarachnoid or ventricular) 0.37 0.23 0.58 0.27 0.13 0.50 0.42 0.26 0.62
Leptomeningeal enhancement 0.34 0.20 0.57 0.30 0.16 0.53 0.32 0.17 0.54
Cranial nerve enhancement 0.45 0.28 0.69 0.19 0.07 0.42 0.68 0.52 0.83
Hydrocephalus 0.09 0.03 0.22 0.11 0.02 0.28 0.06 -0.03 0.22
Parenchymal (brain metastases) 0.54 0.37 0.75 0.45 0.28 0.66 0.57 0.39 0.76
Spine
Nodules (subarachnoid) 0.35 0.21 0.56 0.23 0.10 0.45 0.52 0.35 0.72
Leptomeningeal enhancement 0.17 0.06 0.42 0.34 0.18 0.58 0.43 0.24 0.70
Nerve root enhancement 0.31 0.17 0.57 0.17 0.05 0.40 0.44 0.27 0.67
Parenchymal (intramedullary metastases) -0.04 -0.05 -0.02 -0.10 -0.11 -0.09 0.08 -0.02 0.29
Epidural metastasis 0.04 -0.01 0.15 0.05 -0.02 0.21 0.28 0.12 0.52

Abbreviations: NO: neuro-oncologist. NR: neuroradiologist, LM-related items are printed in bold.