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. 2019 Jan 23;21(5):648–658. doi: 10.1093/neuonc/noz024

Table 4.

Overall concordance rates for the 3 composite change scores determined using ICC

A. Including All Raters
NO + NR (n =19) NO (n = 10) NR (n =9)
Item ICC LCL UCL ICC LCL UCL ICC LCL UCL
Change score 1 0.48 0.32 0.70 0.35 0.18 0.59 0.66 0.50 0.81
Change score 2 0.48 0.33 0.66 0.37 0.22 0.58 0.59 0.43 0.76
Change score 3 0.48 0.34 0.67 0.37 0.23 0.58 0.59 0.44 0.76
B. Excluding the 2 Outlier Raters
NO + NR (n = 17) NO (n = 8)
Item ICC LCL UCL ICC LCL UCL
Change score 1 0.60 0.44 0.79 0.58 0.39 0.78
Change score 2 0.57 0.42 0.74 0.55 0.39 0.74
Change score 3 0.58 0.43 0.75 0.56 0.40 0.74

Abbreviations: ICC intraclass correlation, LCL, lower 95% confidence limit, UCL: upper 95% confidence limit.

Total score 1: as rated by the participants.

Total score 2: as corrected according to LANO proposal with 7 items (brain nodules, brain leptomeningeal enhancement, cranial nerve enhancement, spinal nodules, spinal leptomeningeal enhancement, nerve root enhancement, and epidural metastases).

Total score 3: as corrected with the 6 leptomeningeal items only (brain nodules, brain leptomeningeal enhancement, cranial nerve enhancement, spinal nodules, spinal leptomeningeal enhancement, and nerve root enhancement).