Fig. 2:

Binge-like ethanol consumption of a 20% (v/v) ethanol solution with DID procedures beginning 30-minutes after administration of vehicle (VEH), BUP alone (20 mg/kg; i.p.), NAL alone (3 mg/kg, i.p.) or combined BUP/NAL (20 mg/kg and 3 mg/kg, respectively; i.p.). Panels A and B show ethanol consumption during the first and second hours of testing, respectively, and panel C shows cumulative ethanol consumption over the 2-hour test. Panel D shows BECs that were assessed immediately after the 2-hour test. Panels E and F show consumption of a 3% (w/v) sucrose solution during the first and second hours of test, respectively, and panel G shows cumulative sucrose consumption over the 2-hour test. Data are presented as means + SEM, and * = p < 0.05 relative to the vehicle group.