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. Author manuscript; available in PMC: 2020 May 6.
Published in final edited form as: Mol Pharm. 2019 Mar 26;16(5):1958–1970. doi: 10.1021/acs.molpharmaceut.8b01319

Table 2.

Physicochemical Properties of NP

Polymer Particle size
(nm)
PDI ζ-potential
(mV)
Drug loading
(wt. %)
EE
(%)
PLGA 5kDa 224 ± 12 0.03 ± 0.02 −6 ± 4 1.1 6.6
PLGA 18kDa 250 ± 12 0.03 ± 0.01 −1.5 ± 0.5 4 24
PLGA 34kDa 265 ± 10 0.03 ± 0.01 −1.2 ± 0.1 6 36
PLGA 54kDa 252 ± 4 0.05 ± 0.03 −1 ± 0.2 7.9 47