Table 3:
Univariable analyses of pre-extracorporeal membrane oxygenation candidate predictors of in-hospital mortality included in the multivariable model
| In-hospital mortality | ||||
|---|---|---|---|---|
| Variable | Odds ratio (95% CI) |
P-value | % Missing pre-imputation |
% Missing post-imputation |
| Primary ECMO indication | <0.001 | 0% | 0% | |
| Respiratory | Reference | |||
| Cardiac | 1.91 (1.30, 2.80) | |||
| eCPR | 3.14 (1.81, 5.46) | |||
| Age | 0.001 | 0% | 0% | |
| Pre-term neonate | 3.71 (1.93, 7.15) | |||
| Full-term neonate | Reference | |||
| Infant | 1.75 (1.11, 2.74) | |||
| Child | 1.43 (0.85, 2.40) | |||
| Adolescent | 1.67 (0.88, 3.19) | |||
| Acute diagnoses | ||||
| Congenital diaphragmatic hernia | 2.03 (1.15, 3.58) | 0.014 | 0% | 0% |
| Meconium aspiration syndrome | 0.10 (0.03, 0.28) | <0.001 | 0% | 0% |
| Infection | ||||
| Level of evidence | ||||
| Documented | 1.34 (0.83, 2.16) | 0.233 | 0% | 0% |
| Pathogen | ||||
| Bacterial | 1.82 (0.99, 3.37) | 0.055 | 0% | 0% |
| Viral | 0.70 (0.35, 1.43) | 0.327 | 0% | 0% |
| System | ||||
| Blood | 3.71 (1.54, 8.93) | 0.003 | 0% | 0% |
| Respiratory | 0.80 (0.46, 1.41) | 0.442 | 0% | 0% |
| Other | 2.44 (0.22, 27.12) | 0.467 | 0% | 0% |
| Labs | ||||
| pH | 0.32 (0.10, 1.02) | 0.054 | 18% | 0% |
| Partial thromboplastin time (seconds) | 1.13 (1.04, 1.22) | 0.003 | 36% | 0% |
| International normalized ratio | 1.99 (1.36, 2.90) | <0.001 | 37% | 0% |
514 records were analyzed in models for in-hospital mortality. Analysis based on non-imputed data.
ECMO = extracorporeal membrane oxygenation; eCPR = extracorporeal cardiopulmonary resuscitation