Table 2.
Specific Activities of Human Organ Cytosols with Hesperetin, Naringenin and Apigenin as Substratesa
| Specific Activity (pmol/min/mg) | |||||
|---|---|---|---|---|---|
| Substrate | Concentration | Lung | Liver | Small intestine | Kidney |
| Hesperetin | 10 μM | 23.31 ± 0.95 | 139.79 ± 6.87 | 458.26 ± 11.82 | 2.83 ± 0.40 |
| 50 μM | 28.60 ± 4.68 | 181.73 ± 13.25 | 643.61 ± 45.12 | 5.66 ± 0.10 | |
| Naringenin | 10 μM | 19.08 ± 1.50 | 135.32 ± 15.67 | 252.86 ± 13.22 | 2.77 ± 0.60 |
| 50 μM | 26.53 ± 0.13 | 156.97 ± 17.94 | 354.21 ± 13.98 | 3.27 ± 1.27 | |
| Apigenin | 10 μM | NDb | 20.87 ± 5.39 | 88.59 ± 1.07 | NDb |
| 50 μM | NDb | 25.04 ± 2.20 | 113.24 ± 0.32 | NDb | |
a
Specific activity refers to pmol substrate sulfated/min/mg protein. Data represent mean ± SD derived from three experiments.
b
ND refers to activity not detected.