. 2019 Apr 29;45(2):51–67. doi: 10.5125/jkaoms.2019.45.2.51

Table 5. Dental bone graft substitutes which was consisted with hydroxyapatite (HA).

Product name	Delivery	Component	Indication	Morphology	Property	Level of evidence
OssaBase-HA	Granule	HA:CaP (1.65), Ca₁₀(Po₄)₆(OH)₂	Remodeling of the alveolar ridge	Macro-nano bone like structure	Volume maintenance	Human study level (IV: GBR22)
			Treatment of periodontal defects	83% interconnected porosity	Low substitution rate	Animal, in vivo , in vitro studies
			Treatment of bone defects around dental implants	Narrow size ranges of available granules	No risk of immunological reactions or pathogen transmission
			Sinus lift	Enough space for bone ingrowth over large distances
			Filling of bone defects after surgical extractions to prevent alveolar atrophy
			Filling of bone defects after extirpation of cysts
Ovis BONE HA	Granule	100% HA	Periodontal bone defect	Well-formed macro/micro porous	Osteoconductivity	NA
			Intrabony defect	Porosity	Biocompatibility
			Extraction site		Non toxicity
			Ridge augmentation		Non inflammatory nature
			Sinus lift		Easy manipulation
			Cystic cavity
CollaOss (Block), Ossbone Collagen	Plug	HA 90%±5%+ collagen 10%±5%	Periodontal bone defect	Well-formed macro/micro porous	Easy manipulation and adhesion due to collagen	Human study (III: extraction socket18, IV: peri-implant defect19)
CollaOss (Block), Ossbone Collagen	Plug	HA 90%±5%+ collagen 10%±5%	Intrabony defect	Porosity	Slow absorption and partial remodeling
CollaOss (Putty)	Granule	HA 90%±5%+collagen 10%±5%	Periodontal bone defect	Well-formed macro/micro porous	Easy manipulation and adhesion due to collagen	Animal study
CollaOss (Putty)	Granule	HA 90%±5%+collagen 10%±5%	Intrabony defect	Porosity	Slow absorption and partial remodeling	Animal study

(CaP: calcium phosphate, GBR: guided bone regeneration, NA: data not available)