Table 2.
The genotype distribution and allele frequencies of MC1R gene SNPs locus
| SNPs | Genotype | Phenotype class | Total | Frequency/% | χ2 value | ||||
|---|---|---|---|---|---|---|---|---|---|
| Black | White | Gray | Black-speckle | Horizontal spot | |||||
| SNP1 (T398A) | TT | 50 (0.2) | 15 (0.06) | 47 (0.188) | 50 (0.2) | 24 (0.096) | 186 | 74.4 |
χ2 = 6.56 p < 0.05 |
| TA | 0 (0) | 26 (0.104) | 3 (0.012) | 0 (0) | 19 (0.076) | 48 | 19.2 | ||
| AA | 0 (0) | 9 (0.036) | 0 (0.00) | 0 (0) | 7 (0.028) | 16 | 6.4 | ||
| Total | 50 | 50 | 50 | 50 | 50 | 250 | 100 | ||
| T | 100 | 56 | 97 | 100 | 67 | 420 | 84.0 | ||
| A | 0 | 44 | 3 | 0 | 33 | 80 | 16.0 | ||
| SNP2 (T637C) | TT | 46 (0.184) | 8 (0.032) | 32 (0.128) | 43 (0.172) | 22 (0.088) | 151 | 60.4 |
χ2 = 7.25 p < 0.05 |
| TC | 4 (0.016) | 29 (0.116) | 14 (0.056) | 6 (0.024) | 18 (0.072) | 71 | 28.4 | ||
| CC | 0 (0.00) | 13 (0.052) | 4 (0.016) | 1 (0.004) | 10 (0.04) | 28 | 11.2 | ||
| Total | 50 | 50 | 50 | 50 | 50 | 250 | 100 | ||
| T | 96 | 45 | 78 | 92 | 62 | 373 | 74.6 | ||
| C | 4 | 55 | 22 | 8 | 38 | 127 | 25.4 | ||
| SNP3 (G920C) | GG | 50 (0.2) | 31 (0.124) | 39 (0.156) | 41 (0.164) | 41 (0.164) | 202 | 80.8 |
χ2 = 6.03 p < 0.05 |
| GC | 0 (0) | 12 (0.048) | 8 (0.032) | 9 (0.036) | 9 (0.036) | 38 | 15.2 | ||
| CC | 0 (0) | 7 (0.028) | 3 (0.012) | 0 (0) | 0 (0.08) | 10 | 4 | ||
| Total | 50 | 50 | 50 | 50 | 50 | 250 | 100 | ||
| G | 100 | 74 | 86 | 91 | 91 | 442 | 88.4 | ||
| C | 0 | 26 | 14 | 9 | 9 | 58 | 11.6 | ||