Table 2.
Transcripts UP-regulated after 2 h at 37 °C.
| Transcript_IDa | log2FC(37/26) | Reference geneb | Descriptionc |
|---|---|---|---|
| Protein folding/stress response | |||
| LmjF.34.T0070 | 1.839 | LmjF.34.0070 | ascorbate peroxidase (APX) |
| LmjF.29.T2450 | 1.327 | LmjF.29.2450 | heat shock protein 20 |
| LmjF.33.T0365 | 1.295 | LmjF.33.0365 | HSP83/90 |
| LmjF.32.T2260 | 1.291 | LmjF.32.2260 | heat shock protein Hsp20 |
| LmjF.29.T1270 | 1.291 | LmjF.29.1270 | HSP100 |
| LmjF.28.T2780 | 1.156 | LmjF.28.2780 | HSP70 (type-I transcript) |
| LmjF.33.T0318 | 1.091 | LmjF.33.0318 | HSP83/90 |
| Nucleosome assembly | |||
| LmjF.17.T1220 | 1.442 | LmjF.17.1220 | histone H2B |
| LmjF.21.T0930 | 1.070 | LmjF.21.0930 | histone H2A |
| Other functions | |||
| LmjF.28.T1570 | 1.232 | LmjF.28.1570 | hydrolase, alpha/beta fold family, putative |
| LmjF.17.T1010 | 1.017 | LmjF.17.1010 | hydrolase, alpha/beta fold family-like protein |
| LmjF.19.T1347 | 1.014 | LmjF.19.1347 | membrane-bound O-acyltransferase, putative |
| LmjF.08.T0700 | 1.003 | LmjF.08.0700 | amastin-like protein |
| Hypothetical proteins | |||
| LmjF.35.T2600 | 1.791 | LmjF.35.2600 | hypothetical protein, unknown function |
| LmjF.35.T2610 | 1.591 | LmjF.35.2610 | hypothetical protein, unknown function |
| LmjF.08.T0860 | 1.515 | LmjF.08.0860 | hypothetical protein, unknown function |
| LmjF.23.T1665 | 1.399 | LmjF.23.1665 | hypothetical protein |
| LmjF.08.T1225 | 1.373 | LmjF.08.1225 | hypothetical protein, unknown function |
| LmjF.05.T0810 | 1.190 | LmjF.05.0810 | hypothetical protein, conserved |
| LmjF.29.T2070 | 1.156 | LmjF.29.2070 | hypothetical protein, unknown function |
| LmjF.31.T0120 | 1.145 | LmjF.31.0120 | hypothetical protein, conserved |
| LmjF.27.T1740 | 1.145 | LmjF.27.1740 | hypothetical protein, unknown function |
| LmjF.12.T1050 | 1.143 | LmjF.12.1050 | hypothetical protein, conserved |
| LmjF.08.T1270 | 1.122 | LmjF.08.1270 | hypothetical protein (amidinotransferase domain) |
| LmjF.12.T0800 | 1.111 | LmjF.12.0800 | hypothetical protein, conserved |
| LmjF.13.T0590 | 1.107 | LmjF.13.0590 | hypothetical protein, conserved |
| LmjF.07.T0745 | 1.105 | LmjF.07.0745 | hypothetical protein |
| LmjF.35.T4240 | 1.066 | LmjF.35.4240 | hypothetical protein, conserved |
| LmjF.12.T0840 | 1.041 | LmjF.12.0840 | hypothetical protein, conserved |
| LmjF.17.T0860 | 1.029 | LmjF.17.0860 | hypothetical protein, unknown function |
| LmjF.36.T4050 | 1.021 | LmjF.36.4050 | hypothetical protein, conserved (TatD related DNase domain) |
| LmjF.28.T1120 | 1.016 | LmjF.28.1120 | hypothetical protein, conserved |
| LmjF.12.T1030 | 1.012 | LmjF.12.1030 | hypothetical protein, conserved |
| Transcripts lacking protein-coding annotation | |||
| LmjF.35.T0095 | 1.651 | — | unknown |
| LmjF.32.T2675 | 1.573 | — | unknown |
| LmjF.15.T0432 | 1.503 | — | unknown |
| LmjF.29.T1832 | 1.351 | — | unknown |
| LmjF.29.T1265 | 1.324 | — | unknown |
| LmjF.10.T0605 | 1.249 | — | unknown |
| LmjF.36.T2285 | 1.232 | — | unknown |
| LmjF.27.T0215 | 1.203 | — | unknown (ORF coding for 117 amino acids) |
| LmjF.01.T0795 | 1.169 | — | unknown (ORF coding for 112 amino acids) |
| LmjF.33.T0537 | 1.097 | — | unknown |
| LmjF.19.T0595 | 1.072 | — | unknown |
| LmjF.36.T5945 | 1.071 | — | unknown |
| LmjF.32.T3345 | 1.058 | — | unknown (ORF coding for 93 amino acids) |
| LmjF.22.T1625 | 1.052 | — | unknown |
| LmjF.26.T0465 | 1.040 | — | unknown |
| LmjF.31.TsnRNA.01 | 1.039 | LmjF.31.snRNA.01 | small nuclear RNA, U2 snRNA |
| LmjF.23.T1595 | 1.034 | — | unknown |
| LmjF.02.T0075 | 1.022 | — | unknown |
| LmjF.08.T1237 | 1.014 | — | unknown |
aTranscript identifier (ID) according to Rastrojo et al.34. Additional information is available at Leish-ESP server (http://leish-esp.cbm.uam.es/).
bGene ID according to GeneDB database.
cHypothetical protein: predicted bioinformatically. Conserved: predicted protein of unknown function that is also annotated in T. brucei and/or T. cruzi genomes (GeneDB.org). Unknown: non-demonstrated protein-coding function.