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. 2019 Apr 30;10:403. doi: 10.3389/fphar.2019.00403

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Copyright © 2019 Tong, Qi, Yang, Li, Wang, Lan, Wang and Yang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of PASE on blood pressure and heart rate after single administration. Systolic (A), diastolic (B), mean blood pressure (C), and heart rat (D) changes of SHR after being singly administrated with PASE. Data are presented by means ± SE; n = 6 per group. Blood pressures and heart rates were analyzed by two-way ANOVA with between (groups) and within (hours) subject factors, and data on each time point were by one-way MANOVA with Bonferroni post hoc test. Labeled means without a common letter differ indicated a significant difference, p < 0.05 (a > b) between groups.