Table 4.
SNPs | Haplotype | Freq (case) | Freq (control) | Without adjusted | With adjusted | ||
---|---|---|---|---|---|---|---|
OR (95% CI) | p a | OR (95% CI) | P a | ||||
rs2274976/rs1801133 | AC | 0.517 | 0.545 | 1.00 | — | 1.00 | — |
GC | 0.424 | 0.390 | 1.16 (1.00–1.35) | 0.057 | 1.26 (1.07–1.47) | 0.005* | |
GT | 0.052 | 0.062 | 0.84 (0.60–1.18) | 0.320 | 0.94 (0.66–1.33) | 0.710 | |
rs1805087/rs2853522 | AC | 0.493 | 0.481 | 1.00 | — | 1.00 | — |
AA | 0.427 | 0.420 | 0.99 (0.85–1.16) | 0.940 | 1.00 (0.85–1.17) | 0.990 | |
GC | 0.080 | 0.100 | 0.78 (0.60–1.02) | 0.069 | 0.82 (0.62–1.09) | 0.170 | |
rs1532268/rs162036 | CA | 0.684 | 0.699 | 1.00 | — | 1.00 | — |
CG | 0.162 | 0.174 | 0.96 (0.78–1.17) | 0.660 | 0.96 (0.78–1.18) | 0.680 | |
TA | 0.153 | 0.128 | 1.20 (0.98–1.48) | 0.078 | 1.17 (0.94–1.45) | 0.150 |
SNP: single nucleotide polymorphism; ORs: odds ratios; 95% CI: 95% confidence interval.
Adjusted by sex and age.
Value of p ≤ 0.05 indicates statistical significance.